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Eeyarestatin ES24

Chemical Structure : Eeyarestatin ES24

CAS No.: 2421159-49-9

Eeyarestatin ES24

Catalog No.: PC-25309Not For Human Use, Lab Use Only.

Eeyarestatin ES24 is a specific inhibitor of p97-dependent protein degradation, Sec61-dependent protein translocation into the endoplasmic reticulum (ER), induces Ca2+-dependent cell death, targets the Sec61 complexes.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Eeyarestatin ES24 is a specific inhibitor of p97-dependent protein degradation, Sec61-dependent protein translocation into the endoplasmic reticulum (ER), induces Ca2+-dependent cell death, targets the Sec61 complexes.

Physicochemical Properties

M.Wt 299.29
Formula C15H13N3O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Benzeneacetic acid, 2-[3-(5-nitro-2-furanyl)-2-propen-1-ylidene]hydrazide

References

1. Gamayun I, et al. Cell Chem Biol. 2019 Apr 18;26(4):571-583.e6.

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