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Chemical Structure : Elafibranor
CAS No.: 923978-27-2
Catalog No.: PC-45067Not For Human Use, Lab Use Only.
Elafibranor (GFT-505) is a potent dual PPAR α/δ agonist with EC50 of 45 and 175 nM, respectively.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg (Free Sample) | $28 | In stock | |
| 25 mg | $128 | In stock | |
| 50 mg | $198 | In stock | |
| 100 mg | $348 | In stock | |
| 250 mg | Get quote |
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Elafibranor (GFT-505) is a potent dual PPAR α/δ agonist with EC50 of 45 and 175 nM, respectively.
Elafibranor (GFT-505) demonstrates liver-protective effects on steatosis, inflammation, and fibrosis in animal models of NAFLD/NASH and liver fibrosis.
Elafibranor (GFT-505) significantly reduces fasting plasma triglycerides and increases HDL cholesterol, also reduces γ glutamyl transferase levels.
| M.Wt | 384.4886 | |
| Formula | C22H24O4S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 33 mg/mL |
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| Chemical Name/SMILES |
Propanoic acid, 2-[2,6-dimethyl-4-[(1E)-3-[4-(methylthio)phenyl]-3-oxo-1-propen-1-yl]phenoxy]-2-methyl- |
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1. Liu ZM, et al. Expert Opin Investig Drugs. 2015 May;24(5):611-21.
2. Cariou B, et al. Diabetes Care. 2011 Sep;34(9):2008-14.
3. Staels B, et al. Hepatology. 2013 Dec;58(6):1941-52.
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