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Elagolix sodium

Chemical Structure : Elagolix sodium

CAS No.: 832720-36-2

Elagolix sodium (NBI-56418 sodium)

Catalog No.: PC-23476Not For Human Use, Lab Use Only.

Elagolix (NBI-56418) sodium is a highly effective, selective, orally bioavailable, non-peptide gonadotropin-releasing hormone receptor (GnRH) antagonist with KD value of 54 pM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Elagolix (NBI-56418) sodium is a highly effective, selective, orally bioavailable, non-peptide gonadotropin-releasing hormone receptor (GnRH) antagonist with KD value of 54 pM.

Physicochemical Properties

M.Wt 653.58
Formula C32H29F5N3NaO5
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Sodium (R)-4-((2-(5-(2-fluoro-3-methoxyphenyl)-3-(2-fluoro-6-(trifluoromethyl)benzyl)-4-methyl-2,6-dioxo-3,6-dihydropyrimidin-1(2H)-yl)-1-phenylethyl)amino)butanoate

References

1. Kim SM, et al. J Med Chem. 2016 Oct 13;59(19):9150-9172. Epub 2016 Sep 27.

2. Chen C, et al. J Med Chem. 2008 Dec 11;51(23):7478-85.

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