Chemical Structure : Elexacaftor
CAS No.:
2216712-66-0
Elexacaftor
(VX-445, WHO11180)
Catalog No. : PC-73172Not For Human Use, Lab Use Only.
Elexacaftor (VX-445) is a next-generation cystic fibrosis transmembrane conductance regulator (CFTR) corrector and modulator for cystic fibrosis treatment.
Packing Price Stock Quantity 1 mg $98 In stock 0 1 2 3 4 5 5 mg $198 In stock 0 1 2 3 4 5 10 mg $298 In stock 0 1 2 3 4 5 25 mg $488 In stock 0 1 2 3 4 5 50 mg $758 In stock 0 1 2 3 4 5 100 mg Get quote 0 1 2 3 4 5
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-7317201
Biological Activity
Elexacaftor (VX-445) is a next-generation cystic fibrosis transmembrane conductance regulator (CFTR ) corrector and modulator for cystic fibrosis treatment.
Physicochemical Properties
M.Wt
597.658
Formula
C26H34F3N7O4S
Appearance
Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
(S)-N-((1,3-Dimethyl-1H-pyrazol-4-yl)sulfonyl)-6-(3-(3,3,3-trifluoro-2,2-dimethylpropoxy)-1H-pyrazol-1-yl)-2-(2,2,4-trimethylpyrrolidin-1-yl)nicotinamide
References
1. Keating D, et al. N Engl J Med.
2. Taylor-Cousar JL, et al. ERJ Open Res.
3. Middleton PG, et al. N Engl J Med.
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