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Chemical Structure : Elobixibat
CAS No.: 439087-18-0
Catalog No.: PC-61407Not For Human Use, Lab Use Only.
Elobixibat (A3309, AZD7806, AJG-533) is an orally available, potent and selective ileal bile acid transporter (IBAT) inhibitor with IC50 of 0.53 nM, 0.13 nM, and 5.8 nM for human, mouse, and canine IBAT respectively.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 2 mg | $358 | In stock | |
| 5 mg | $598 | In stock | |
| 10 mg | $958 | In stock | |
| 25 mg | Get quote |
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Elobixibat (A3309, AZD7806, AJG-533) is an orally available, potent and selective ileal bile acid transporter (IBAT) inhibitor with IC50 of 0.53 nM, 0.13 nM, and 5.8 nM for human, mouse, and canine IBAT respectively.
| M.Wt | 695.89 | |
| Formula | C36H45N3O7S2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
Glycine, (2R)-N-[[[3,3-dibutyl-2,3,4,5-tetrahydro-7-(methylthio)-1,1-dioxido-5-phenyl-1,5-benzothiazepin-8-yl]oxy]acetyl]-2-phenylglycyl- (9CI) |
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1. Chey WD, et al. Gastroenterol. 2014 May;109(5):782.
2. Wong BS, et al. Expert Opin Investig Drugs. 2013 Feb;22(2):277-84.
3. Wong BS, et al. Am J Gastroenterol. 2011 Dec;106(12):2154-64.
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