| Cat. No. |
Product Name |
Information |
| PC-63549 |
Lopixibat chloride
IBAT inhibitor
|
Lopixibat chloride (LUM-001, HP-625) is a potent, selectiove, oral inhibitor of sodium bile acid cotransporter and Ileal bile acid transporter (IBAT).. |
| PC-63453 |
A4250
IBAT inhibitor
|
A4250 (A-4250, Odevixibat) is a small molecule ileal bile acid transporter (IBAT) inhibitor for the treatment of cholestatic liver diseases including progressive familial intrahepatic cholestasis and NASH.. |
| PC-61418 |
Volixibat
ASBT inhibitor
|
Volixibat (SHP-626;SAR-548304;LUM-002) is a highly potent and selective inhibitor of the apical sodium-dependent bile acid transporter (ASBT) in development for the treatment of nonalcoholic steatohepatitis (NASH). |
| PC-61407 |
Elobixibat
IBAT inhibitor
|
Elobixibat (A3309, AZD7806, AJG-533) is an orally available, potent and selective ileal bile acid transporter (IBAT) inhibitor with IC50 of 0.53 nM, 0.13 nM, and 5.8 nM for human, mouse, and canine IBAT respectively. |
| PC-61384 |
Linerixibat
ASBT inhibitor
|
Linerixibat (GSK2330672) is a highly potent, selective, ileal apical sodium-dependent bile acid transporter (ASBT) inhibitor with IC50 of 2.1/1.9 nM for mouse/rat ASBT, respectively. |
| PC-20411 |
A3907
ASBT inhibitor
|
A3907 is an apical sodium-dependent bile acid transporter (ASBT) inhibitor. |
| PC-61419 |
Volixibat potassium
|
A highly potent and selective inhibitor of the apical sodium-dependent bile acid transporter (ASBT) in development for the treatment of nonalcoholic steatohepatitis (NASH).. |
