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Maralixibat chloride

Chemical Structure : Maralixibat chloride

CAS No.: 228113-66-4

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Maralixibat chloride (Lopixibat chloride, LUM-001, HP-625)

Catalog No.: PC-63549Not For Human Use, Lab Use Only.

Maralixibat chloride (Lopixibat chloride, LUM-001, HP-625) is a potent, selective, oral inhibitor of apical sodium-dependent bile acid transporter (ASBT, ileal bile acid transporter (IBAT) and SLC10A2).

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Maralixibat chloride (Lopixibat chloride, LUM-001, HP-625) is a potent, selective, oral inhibitor of apical sodium-dependent bile acid transporter (ASBT, ileal bile acid transporter (IBAT) and SLC10A2).

Physicochemical Properties

M.Wt 710.415
Formula C40H56ClN3O4S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

1-(4-((4-((4R,5R)-3,3-dibutyl-7-(dimethylamino)-4-hydroxy-1,1-dioxido-2,3,4,5-tetrahydrobenzo[b]thiepin-5-yl)phenoxy)methyl)benzyl)-1,4-diazabicyclo[2.2.2]octan-1-ium chloride

References

1. Wannowius M, et al. J Med Chem. 2024 Nov 14;67(21):19342-19364.

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