S1647

Chemical Structure : S1647

Catalog No.: PC-23585Not For Human Use, Lab Use Only.

S1647 is a nonselective, multitarget inhibitor of intestinal bile acid carrier ASBT (SLC10A2), steroid sulfate carrier SOAT (SLC10A6) and hepatic bile acid carrier NTCP (SLC10A1) with IC50 of SOAT, ASBT, and NTCP of 13.4 3.5, and 10.4 μM, respectively.

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Biological Activity

Physicochemical Properties

M.Wt	466.29
Formula	C19H13Cl2N3O5S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(3,4-Dichlorophenyl)-2-[[(3-nitrophenyl)sulfonyl]amino]benzamide

References

1. Wannowius M, et al. J Med Chem. 2024 Nov 14;67(21):19342-19364.

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S1647

Biological Activity

Physicochemical Properties

References

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