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Chemical Structure : Emodepside
CAS No.: 155030-63-0
Catalog No.: PC-42397Not For Human Use, Lab Use Only.
A semisynthetic derivative of PF1022A, and novel cyclo-depsipeptide anthelmintic which is efficacious against a variety of gastrointestinal nematodes.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $224 | In stock | |
| 50 mg | $704 | In stock | |
| 100 mg | $1160 | In stock |
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A semisynthetic derivative of PF1022A, and novel cyclo-depsipeptide anthelmintic which is efficacious against a variety of gastrointestinal nematodes; causes parasitic nematode muscle relaxation, inhibition of muscle contraction elicited by either ACh or the neuropeptide AF2; elicits a Ca(++)-dependent hyperpolarization of muscle cells.
Parasite Infection
Phase 1 Clinical
| M.Wt | 1119.3884 | |
| Formula | C60H90N6O14 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 31 mg/mL |
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| Chemical Name/SMILES |
Cyclo[(αR)-α-hydroxy-4-(4-morpholinyl)benzenepropanoyl-N-methyl-L-leucyl-(2R)-2-hydroxypropanoyl-N-methyl-L-leucyl-(αR)-α-hydroxy-4-(4-morpholinyl)benzenepropanoyl-N-methyl-L-leucyl-(2R)-2-hydroxypropanoyl-N-methyl-L-leucyl] |
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1. Harder A, Parasitol Res. 2001 Nov;87(11):924-8.
2. Harder A, et al. Parasitol Res. 2002 Jun;88(6):481-8.
3. Willson J, et al. Parasitology. 2003 Jan;126(Pt 1):79-86.
4. Harder A, et al. Int J Antimicrob Agents. 2003 Sep;22(3):318-31.
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