Chemical Structure : Enclomiphene citrate
CAS No.: 7599-79-3
Catalog No.: PC-60063Not For Human Use, Lab Use Only.
Enclomiphene citrate ((E)-Clomifene, cis-Clomifene, RMI-16289, ICI-46476) is a nonsteroidal selective estrogen receptor modulator (SERM) that is under development for the treatment of male hypogonadism.
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Enclomiphene citrate ((E)-Clomifene, cis-Clomifene, RMI-16289, ICI-46476) is a nonsteroidal selective estrogen receptor modulator (SERM) that is under development for the treatment of male hypogonadism.
Enclomiphene citrate inhibits the ER in the pituitary gland, reduces negative feedback by estrogen on the hypothalamic-pituitary-gonadal axis, increases gonadotropin secretion and hence gonadal production of testosterone.
M.Wt | 598.089 | |
Formula | C32H36ClNO8 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
(E)-2-(4-(2-chloro-1,2-diphenylvinyl)phenoxy)-N,N-diethylethan-1-amine 2-hydroxypropane-1,2,3-tricarboxylate |
1. Hill S, et al. IDrugs. 2009 Feb;12(2):109-19.
2. Marth C, et al. Biochem Pharmacol. 1984 Dec 15;33(24):3951-6.
3. Wilcox JN, et al. Brain Res. 1983 May 5;266(2):243-51.
4. Huang ES, et al. Endocrinology. 1983 Feb;112(2):442-8.
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