Catalog No.: PC-70343Not For Human Use, Lab Use Only.
EGA is a potent anthrax lethal toxin entry inhibitor with IC50 of 1.7 uM, inhibits endosomal trafficking pathways exploited by multiple toxins and viruses.
EGA is a potent anthrax lethal toxin entry inhibitor with IC50 of 1.7 uM, inhibits endosomal trafficking pathways exploited by multiple toxins and viruses.
EGA also delays lysosomal targeting and degradation of the EGF receptor, does not neutralize acidic organelles.
EGA is a powerful tool for the study of membrane trafficking and represents a class of host-targeted compounds for therapeutic development to treat infectious disease.
