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Endoxifen

Chemical Structure : Endoxifen

CAS No.: 112093-28-4

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Endoxifen (Endoxifen (Z-isomer))

Catalog No.: PC-45540Not For Human Use, Lab Use Only.

Endoxifen is a metabolite of tamoxifen, orally active non-steroidal selective estrogen receptor modulator (SERM) for the treatment of estrogen receptor-positive breast cancer.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Endoxifen (Endoxifen (Z-isomer)) is a metabolite of tamoxifen, orally active non-steroidal selective estrogen receptor modulator (SERM) for the treatment of estrogen receptor-positive breast cancer.

Physicochemical Properties

M.Wt 373.4874
Formula C25H27NO2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

Phenol, 4-[(1Z)-1-[4-[2-(methylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]-

References

1. Brauch H, et al. Clin Chem. 2009 Oct;55(10):1770-82.

2. Markopoulos C, et al. World J Clin Oncol. 2014 Aug 10;5(3):374-81.

3. Mugundu GM, et al. Drug Metab Dispos. 2012 Feb;40(2):389-96.

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