Envometinib

Chemical Structure : Envometinib

Catalog No.: PC-25048Not For Human Use, Lab Use Only.

Envometinib (Compound 274) is a potent, selective dual MEK1/2 inhibitor, inhibits both pERK and pMEK in RAS mutant and NF-I loss of function (LoF) tumor models.

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Biological Activity

Envometinib (Compound 274) is a potent, selective dual MEK1/2 inhibitor, inhibits both pERK and pMEK in RAS mutant and NF-I loss of function (LoF) tumor models.

Physicochemical Properties

M.Wt	523.00
Formula	C23H27ClN4O6S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	3-(2-chloro-3-((N-methylsulfamoyl)amino)benzyl)-4-((dimethylamino)methyl)-2-oxo-2H-chromen-7-yl dimethylcarbamate

References

1. Patent WO2024102859 A1.

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Envometinib

Biological Activity

Physicochemical Properties

References

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