Chemical Structure : Erdafitinib
CAS No.:
1346242-81-6
Erdafitinib
(JNJ-42756493)
Catalog No. : PC-45537Not For Human Use, Lab Use Only.
Erdafitinib (JNJ-42756493) is a highly potent and selective, small-molecule inhibitor of FGFR family with IC50s of 1.2/2.5/3/5.7 nM for FGFR1/2/3/4.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4553701
Biological Activity
Erdafitinib (JNJ-42756493) is a highly potent and selective, small-molecule inhibitor of FGFR family with IC50s of 1.2/2.5/3/5.7 nM for FGFR1/2/3/4.
Physicochemical Properties
M.Wt
446.5447
Formula
C25H30N6O2
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
DMSO: ≥ 33 mg/mL
Chemical Name/SMILES
1,2-Ethanediamine, N1-(3,5-dimethoxyphenyl)-N2-(1-methylethyl)-N1-[3-(1-methyl-1H-pyrazol-4-yl)-6-quinoxalinyl]-
References
1. Perera TPS, et al. Mol Cancer Ther.
2. Karkera JD, et al. Mol Cancer Ther.
3. Verstraete M, et al. BMC Cancer.
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