Chemical Structure : Ethylisopropylamiloride
CAS No.: 1154-25-2
Catalog No.: PC-28233Not For Human Use, Lab Use Only.
Ethylisopropylamiloride (EIPA) is specific macropinocytosis inhibitor that inhibits endocytosis via the macropinocytic pathway, also inhibits TRPP3-mediated Ca2+-activated currents with IC50 of 10.5 uM, inhibits epithelial sodium channels (ENaC) as well as of several other Na+/H+ antiporters.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $78 | In stock | |
| 25 mg | $128 | In stock | |
| 50 mg | $198 | In stock | |
| 100 mg | Get quote |
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Ethylisopropylamiloride (EIPA) is specific macropinocytosis inhibitor that inhibits endocytosis via the macropinocytic pathway, also inhibits TRPP3-mediated Ca2+-activated currents with IC50 of 10.5 uM, inhibits epithelial sodium channels (ENaC) as well as of several other Na+/H+ antiporters.
| M.Wt | 299.76 | |
| Formula | C11H18ClN7O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
3-Amino-N-carbamimidoyl-6-chloro-5-(ethyl(isopropyl)amino)pyrazine-2-carboxamide |
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1. Nakase I, et al. Mol Ther. 2004 Dec;10(6):1011-22.
2. Dai XQ, et al. Mol Pharmacol. 2007 Dec;72(6):1576-85.
3. Mercer J, et al. Nat Cell Biol. 2009;11:510–520.

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