Evategrel | P2Y12 antagonist | Probechem Biochemicals

Chemical Structure : Evategrel

Evategrel (CG-0255, CG0255)

Catalog No.: PC-24952Not For Human Use, Lab Use Only.

Evategrel (CG-0255) is a novel fast-acting antiplatelet and irreversible P2Y12 receptor antagonistis a prodrug that depends critically on liver CYP oxidation enzyme CYP2C19 for activation.

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Biological Activity

Evategrel (CG-0255) is a novel fast-acting antiplatelet and irreversible P2Y12 receptor antagonistis a prodrug that depends critically on liver CYP oxidation enzyme CYP2C19 for activation.

Physicochemical Properties

M.Wt	471.95
Formula	C21H26ClNO7S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(Z)-2-((R)-1-((S)-1-(2-chlorophenyl)-2-methoxy-2-oxoethyl)-4-((((isopropoxycarbonyl)oxy)methyl)thio)piperidin-3-ylidene)acetic acid

References

1. Patent WO2022022559 A1.

2. X Chen, et al. European Heart Journal, Volume 45, Issue Supplement_1, October 2024.

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Evategrel (CG-0255, CG0255)

Biological Activity

Physicochemical Properties

References

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