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Chemical Structure : Everolimus
CAS No.: 159351-69-6
Catalog No.: PC-42463Not For Human Use, Lab Use Only.
Everolimus (RAD001) is a potent, highly specific, orally active mTOR inhibitor with IC50 of 5-6 nM for binding to FKBP-12 or FKBP-12 complexed to mTOR.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 25 mg | $128 | In stock | |
| 100 mg | $298 | In stock | |
| 200 mg | Get quote | ||
| 1 g | Get quote | ||
| 5 g | Get quote |
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Everolimus (RAD001) is a potent, highly specific, orally active mTOR inhibitor with IC50 of 5-6 nM for binding to FKBP-12 or FKBP-12 complexed to mTOR.
Everolimus (RAD001) inhibits proliferation in vitro (IC50=1 nM-1 uM) in sensitive and insensitive tumor.
Everolimus (RAD001) dose-dependently inhibits tumor growth in vivo.
| M.Wt | 958.2244 | |
| Formula | C53H83NO14 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 54 mg/mL |
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| Chemical Name/SMILES |
Rapamycin, 42-O-(2-hydroxyethyl)- |
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1. Sedrani R, et al. Transplant Proc. 1998 Aug;30(5):2192-4.
2. Schuler W, et al. Transplantation. 1997 Jul 15;64(1):36-42.
3. Lane HA, et al. Clin Cancer Res. 2009 Mar 1;15(5):1612-22.
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