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Evodiamine

Chemical Structure : Evodiamine

CAS No.: 518-17-2

Evodiamine ((+)-Evodiamine)

Catalog No.: PC-27258Not For Human Use, Lab Use Only.

Evodiamine ((+)-Evodiamine) is a natural alkaloid derived from Evodiae Fructus with promising antitumor activity, is a heat shock protein 90 (Hsp90) inhibitor, also exhibits a potential binding interaction with Dickkopf 2 (DKK2), suppresses the Wnt/β-catenin signaling pathway in osteosarcoma cells, suppresses cancer cell proliferation through the induction of apoptosis and cell cycle arrest.

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100 mg $38 In stock
250 mg $58 In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Evodiamine ((+)-Evodiamine) is a natural alkaloid derived from Evodiae Fructus with promising antitumor activity, is a heat shock protein 90 (Hsp90) inhibitor, also exhibits a potential binding interaction with Dickkopf 2 (DKK2), suppresses the Wnt/β-catenin signaling pathway in osteosarcoma cells, suppresses cancer cell proliferation through the induction of apoptosis and cell cycle arrest.

Physicochemical Properties

M.Wt 303.37
Formula C19H17N3O
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(S)-14-Methyl-7,8,13b,14-tetrahydroindolo[2',3':3,4]pyrido[2,1-b]quinazolin-5(13H)-one

References

1. Sun Y, et al. J Med Chem. 2026 Jul 9;69(13):15132-15148.

2. Sun Y, et al, Phytomedicine. 2026 Jun 15;159:158436.

3. Li R, et al. Front Med (Lausanne). 2026 Apr 30;13:1767391.

4. Yang S, et al. Cancer Manag Res. (2020) 12:2875–88.

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