Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
    English |     Chinese

Product Inquiry: sales@probechem.com
Order/PO receiving: order@probechem.com

You are here:Home-Chemical Inhibitors & Agonists-Metabolic Enzyme/Protease-Dipeptidyl Peptidase (DPP)-Evogliptin
Evogliptin

Chemical Structure : Evogliptin

CAS No.: 1222102-29-5

Add to Favorites

Evogliptin (DA-1229;DA1229)

Catalog No.: PC-61445Not For Human Use, Lab Use Only.

Evogliptin (DA1229) is a potent, long acting, reversible and competitive DPP-4 inhibitor with IC50 of 0.9 nM.

Packing Price Stock Quantity
5 mg Get quote
10 mg Get quote
25 mg Get quote
100 mg Get quote
Get Quotation Now
* Please select Quantity before adding items.
 or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    Evogliptin (DA1229) is a potent, long acting, reversible and competitive DPP-4 inhibitor with IC50 of 0.9 nM.
    Evogliptin (DA1229) displays >600-fold selectivity over DPP8 and DPP9.
    Evogliptin (DA1229) increases levels of plasma GLP-1 and insulin, and lowers blood glucose levels in mice (0.1-3 mg/kg).

    Physicochemical Properties

    M.Wt 401.43
    Formula C19H26F3N3O3
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    (3R)-4-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl]-3-[(2-methylpropan-2-yl)oxymethyl]piperazin-2-one

    References

    1. Kim MK, et al. Life Sci. 2012 Jan 2;90(1-2):21-9.

    2. Kim HJ, et al. Bioorg Med Chem Lett. 2011 Jun 15;21(12):3809-12.

    3. Kim TH, et al. Eur J Pharmacol. 2016 Jan 15;771:65-76.

    4. Chae YN, et al. PLoS One. 2015 Dec 3;10(12):e0144064.

    Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

    Contact Us sales@probechem.com

    Bulk Inquiry

    * Indicates a Required FieldYour information is safe with us.

    • *Product name:
    • *Applicant name:
    • *Email address:
    • *Organization name:
    • *Requested quantity:
    • *Country:
    • *Additional Information:

    Get Quote

    * Indicates a Required FieldYour information is safe with us.

    • *Product name:
    • *Applicant name:
    • *Email address:
    • *Organization name:
    • *Requested quantity:
    • *Country:
    • Additional Information: