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Chemical Structure : Ezeprogind
CAS No.: 1616671-13-6
Catalog No.: PC-38099Not For Human Use, Lab Use Only.
Ezeprogind (AZP2006) is a lysotropic molecule with neuroprotective effects, binds to PGRN/PSAP complex with higher affinity (Kd=201 nM) than PSAP (Kd=624 nM), inhibits TLR9 receptors.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $228 | In stock | |
| 10 mg | $398 | In stock | |
| 50 mg | $858 | In stock | |
| 100 mg | $1380 | In stock | |
| 200 mg | Get quote | ||
| 1 g | Get quote |
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Ezeprogind (AZP2006) is a lysotropic molecule with neuroprotective effects, binds to PGRN/PSAP complex with higher affinity (Kd=201 nM) than PSAP (Kd=624 nM), inhibits TLR9 receptors.
AZP2006 prevents neuronal death induced by Aβ injury, and reduces the associated microglial activation in rat cortical neurons.
AZP2006 prevent Aβ25-35 damages in AD mice model.
AZP2006 significantly improved senescence behavior and markers in SAMP8 mice.
| M.Wt | 624.813 | |
| Formula | C25H48N6O8S2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
N-(3-(4-(3-(Diisobutylamino)propyl)piperazin-1-yl)propyl)-1H-benzo(d)imidazol-2-amine, sulfuric acid (1:2) |
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1. N Callizot, et al. Sci Rep. 2021 Aug 19;11(1):16806.
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