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F059-1017

Chemical Structure : F059-1017

CAS No.:

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F059-1017

Catalog No.: PC-24041Not For Human Use, Lab Use Only.

F059-1017 is a potent, selective CDK8 inhibitor with IC50 of 558.1 nM, reduces phosphorylation and expression of signaling mediators associated with inflammation.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

F059-1017 is a potent, selective CDK8 inhibitor with IC50 of 558.1 nM, reduces phosphorylation and expression of signaling mediators associated with inflammation.

Physicochemical Properties

M.Wt 339.41
Formula C19H17NO3S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

3-cyclopentylidene-5-(phenylsulfonyl)indolin-2-one

References

1. Lin TE, et al. Biomed Pharmacother. 2022 Feb;146:112459.

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