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Chemical Structure : F114
Catalog No.: PC-73347Not For Human Use, Lab Use Only.
F114 is a novel, first-in-class, dual aurora and lim kinase (LIMK) inhibitor with IC50 of 72 nM and 137 nM against Aurora-A and Limk1, respectively, F114 inhibits GBM proliferation and invasion.
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F114 is a novel, first-in-class, dual aurora and lim kinase (LIMK) inhibitor with IC50 of 72 nM and 137 nM against Aurora-A and Limk1, respectively, F114 inhibits GBM proliferation and invasion.
| M.Wt | 312.377 | |
| Formula | C16H20N6O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Matthew J Rybin, et al. Bioorg Med Chem Lett. 2022 Apr 1;61:128614.
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