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Chemical Structure : F759
Catalog No.: PC-20736Not For Human Use, Lab Use Only.
F759 is a nonpeptidic small-molecule cyclophilin inhibitor, inhibits coagulation induced by procoagulant platelets.
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F759 is a nonpeptidic small-molecule cyclophilin inhibitor, inhibits coagulation induced by procoagulant platelets.
F759 has potent and specific inhibitory activity against CypA, CypB, and CypD.
F759 prevents mPTP opening in mitochondria from primary human and mouse hepatocytes and protected mice from liver ischemia-reperfusion injury upon binding catalytic and gatekeeper pockets of CypD.
| M.Wt | 474.62 | |
| Formula | C27H30N4O2S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Jens Van Bael, et al. Int J Mol Sci. 2023 Apr 12;24(8):7163.
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