FAUC 1104 |CAS:1869983-86-7 Probechem Biochemicals

Chemical Structure : FAUC 1104

FAUC 1104 (FAUC1104;FAUC-1104)

Catalog No.: PC-61171Not For Human Use, Lab Use Only.

FAUC 1104 is a potent, biased allosteric agonist of CXCR3 (pEC50=5.22) that activates solely G proteins, induces chemotaxis, but fails to induce receptor internalization or β-arrestin 2 recruitment.

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Biological Activity

FAUC 1104 is a potent, biased allosteric agonist of CXCR3 (pEC50=5.22) that activates solely G proteins, induces chemotaxis, but fails to induce receptor internalization or β-arrestin 2 recruitment.

Physicochemical Properties

M.Wt	774.959
Formula	C46H54N4O7
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	tert-Butyl {(S)-1-[(2,2-diphenylethyl)amino]-6-[(S)-2-(4-(4-methoxyphenyl)-4-oxobutanoyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamido]-1-oxohexan-2-yl}carbamate

References

1. Milanos L, et al. J Med Chem. 2016 Mar 10;59(5):2222-43.

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FAUC 1104 (FAUC1104;FAUC-1104)

Biological Activity

Physicochemical Properties

References

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