FEN1-IN-4

Chemical Structure : FEN1-IN-4

CAS No.: 1995893-58-7

Catalog No.: PC-21871Not For Human Use, Lab Use Only.

FEN1-IN-4 is a specific, competitive inhibitor of human flap endonuclease-1 (hFEN1) with IC50 of 30 nM, binds to atalytic metals and blocks DNA unpairing.

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Biological Activity

FEN1-IN-4 is a specific, competitive inhibitor of human flap endonuclease-1 (hFEN1) with IC50 of 30 nM, binds to atalytic metals and blocks DNA unpairing.

Physicochemical Properties

M.Wt	232.24
Formula	C12H12N2O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1-(Cyclopropylmethyl)-3-hydroxyquinazoline-2,4(1H,3H)-dione

References

1. Jack C Exell, et al. Nat Chem Biol. 2016 Oct;12(10):815-21.

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FEN1-IN-4

Biological Activity

Physicochemical Properties

References

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