Catalog No.: PC-28085Not For Human Use, Lab Use Only.
FG-7142 (FG 7142, ZK 39106, LSU-65) is an anxiogenic benzodiazepine inverse agonist / antagonist, has high affinity for α1 subunit-containing GABAA receptor with Ki of 91 nM, also modulates GABA-induced chloride flux at GABAA receptors expressing the α1 subunit with EC50 of 137 nM.
FG-7142 (FG 7142, ZK 39106, LSU-65) is an anxiogenic benzodiazepine inverse agonist / antagonist, has high affinity for α1 subunit-containing GABAA receptor with Ki of 91 nM, also modulates GABA-induced chloride flux at GABAA receptors expressing the α1 subunit with EC50 of 137 nM.
Physicochemical Properties
M.Wt
225.25
Formula
C13H11N3O
Appearance
Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
N-Methyl-9H-pyrido[3,4-b]indole-3-carboxamide
References
1. Petersen EN, et al. Eur J Pharmacol. 1982 Aug 27;82(3-4):217-21.
2. Rossier J, et al. Lancet. 1983 Jan 1;1(8314-5):77-8.
3. Ongini E, et al. Eur J Pharmacol. 1983 Nov 11;95(1-2):125-9.
4. Cottone P, et al. Neuropsychopharmacology. 2007 May;32(5):1069-81.
