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Chemical Structure : FGFR2 inhibitor 38
Catalog No.: PC-72306Not For Human Use, Lab Use Only.
FGFR2 inhibitor 38 is a potent, selective FGFR2 inhibitor with IC50 of 29 nM, exhibits moderate selectivity for FGFR2 over FGFR1/3 (>13.4 fold).
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FGFR2 inhibitor 38 is a potent, selective FGFR2 inhibitor with IC50 of 29 nM, exhibits moderate selectivity for FGFR2 over FGFR1/3 (>13.4 fold).
FGFR2 inhibitor 38 exhibited modest potency against SUM52 cell with an IC50 value of 700 nM.
| M.Wt | 370.456 | |
| Formula | C23H22N4O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Lewis D Turner, et al. J Med Chem. 2022 Jan 27;65(2):1481-1504.
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