Chemical Structure : FGI-106
CAS No.: 501081-38-5
Catalog No.: PC-62053Not For Human Use, Lab Use Only.
FGI-106 is a broad-spectrum inhibitor of multiple blood-borne viruses (HCV, HBV, HIV) as well as emerging biothreats (Ebola, VEE, Cowpox, PRRSV infection) with EC50 of 0.2-10 uM.
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FGI-106 is a broad-spectrum inhibitor of multiple blood-borne viruses (HCV, HBV, HIV) as well as emerging biothreats (Ebola, VEE, Cowpox, PRRSV infection) with EC50 of 0.2-10 uM.
FGI-106 inhibits the interaction of TSG101 with its cognate viral ligands.
FGI-106 displays an ability to prevent lethality from Ebola in vivo; well-tolerated and orally bioavailable.
M.Wt | 458.654 | |
Formula | C28H38N6 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
Quino[8,7-h]quinoline-1,7-diamine, N,N'-bis[3-(dimethylamino)propyl]-3,8-dimethyl- (9CI) |
1. Kinch MS, et al. Am J Transl Res. 2009 Jan 5;1(1):87-98.
2. De Clercq E. Med Res Rev. 2013 Nov;33(6):1249-77.
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