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FH1

Chemical Structure : FH1

CAS No.: 2719-05-3

FH1 (NSC12407, BRD-K4477)

Catalog No.: PC-42996Not For Human Use, Lab Use Only.

FH1 (BRDK4477) is a small molecule that increase function and proliferation of primary human hepatocytes, promotes the differentiation of iPS-derived hepatocytes.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

FH1 (BRDK4477) is a small molecule that increase function and proliferation of primary human hepatocytes, promotes the differentiation of iPS-derived hepatocytes.
FH1 (BRDK4477)  increases the CYP3A4 and CYP2A6 activity
FH1 (BRDK4477)  also increases ~4-fold expression levels of ABC transporter ABCB11 in hepatocytes.

Physicochemical Properties

M.Wt 282.337
Formula C17H18N2O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: 13 mg/mL

Chemical Name/SMILES

Acetamide, N,N'-(methylenedi-4,1-phenylene)bis-

References

1. Shan J, et al. Nat Chem Biol. 2013 Aug;9(8):514-20.

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