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FHND6081

Chemical Structure : FHND6081

CAS No.: 1965226-29-2

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FHND6081 (FHND 6081, FHND-6081)

Catalog No.: PC-22651Not For Human Use, Lab Use Only.

FHND6081 is a potent, selective oral proteasome inhibitor, binds irreversibly to the β5 submit of the 20S proteasome and exerts anti-cancer activities.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

FHND6081 is a potent, selective oral proteasome inhibitor, binds irreversibly to the β5 submit of the 20S proteasome and exerts anti-cancer activities.

Physicochemical Properties

M.Wt 421.14
Formula C16H23BCl2N2O4S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

((R)-1-((S)-2-(2,5-dichlorobenzamido)-3-(methylthio)propanamido)-3-methylbutyl)boronic acid

References

1. Xu Yang, et al. Drug Des Devel Ther. 2022 Sep 13:16:3087-3107.

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