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FHND6091

Chemical Structure : FHND6091

CAS No.: 2266581-04-6

FHND6091 (FHND 6091, FHND-6091)

Catalog No.: PC-22652Not For Human Use, Lab Use Only.

FHND6091 is the prodrug of FHND6081, which is a potent, selective oral proteasome inhibitor, binds irreversibly to the β5 submit of the 20S proteasome and exerts anti-cancer activities.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

FHND6091 is the prodrug of FHND6081, which is a potent, selective oral proteasome inhibitor, binds irreversibly to the β5 submit of the 20S proteasome and exerts anti-cancer activities.

Physicochemical Properties

M.Wt 490.25
Formula C20H30BCl2N3O4S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-((S)-1-(((R)-1-(1,3,6,2-dioxazaborocan-2-yl)-3-methylbutyl)amino)-3-(methylthio)-1-oxopropan-2-yl)-2,5-dichlorobenzamide

References

1. Xu Yang, et al. Drug Des Devel Ther. 2022 Sep 13:16:3087-3107.

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