FHND6091 | Proteasome inhibitor | Probechem Biochemicals

Chemical Structure : FHND6091

FHND6091 (FHND 6091, FHND-6091)

Catalog No.: PC-22652Not For Human Use, Lab Use Only.

FHND6091 is the prodrug of FHND6081, which is a potent, selective oral proteasome inhibitor, binds irreversibly to the β5 submit of the 20S proteasome and exerts anti-cancer activities.

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Biological Activity

FHND6091 is the prodrug of FHND6081, which is a potent, selective oral proteasome inhibitor, binds irreversibly to the β5 submit of the 20S proteasome and exerts anti-cancer activities.

Physicochemical Properties

M.Wt	490.25
Formula	C20H30BCl2N3O4S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N-((S)-1-(((R)-1-(1,3,6,2-dioxazaborocan-2-yl)-3-methylbutyl)amino)-3-(methylthio)-1-oxopropan-2-yl)-2,5-dichlorobenzamide

References

1. Xu Yang, et al. Drug Des Devel Ther. 2022 Sep 13:16:3087-3107.

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FHND6091 (FHND 6091, FHND-6091)

Biological Activity

Physicochemical Properties

References

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