Chemical Structure : FIIN-2
CAS No.:
1633044-56-0
FIIN-2
(FIIN2;FIIN 2)
Catalog No. : PC-45474Not For Human Use, Lab Use Only.
FIIN-2 is a potent, irreversible inhibitor of FGFR with IC50 values of 3.1/ 4.3/27/45 nM for FGFR1/2/3/4.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4547401
Biological Activity
FIIN-2 is a potent, irreversible inhibitor of FGFR with IC50 values of 3.1/ 4.3/27/45 nM for FGFR1/2/3/4.
Physicochemical Properties
M.Wt
634.7274
Formula
C35H38N8O4
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
DMSO: ≥ 30 mg/mL
Chemical Name/SMILES
2-Propenamide, N-[4-[[3-(3,5-dimethoxyphenyl)-3,4-dihydro-7-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-2-oxopyrimido[4,5-d]pyrimidin-1(2H)-yl]methyl]phenyl]-
References
1. Huang Z, et al. ACS Chem Biol.
2. Tan L, et al. Proc Natl Acad Sci U S A.
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