Catalog No.: PC-62636Not For Human Use, Lab Use Only.
FL-411 is a novel small-molecule inhibitor of BRD4, induces ATG5-dependent autophagy-associated cell death (ACD) by blocking BRD4-AMPK interaction and activating AMPK-mTOR-ULK1-modulated autophagic pathway in breast cancer cells.
FL-411 is a novel small-molecule inhibitor of BRD4, induces ATG5-dependent autophagy-associated cell death (ACD) by blocking BRD4-AMPK interaction and activating AMPK-mTOR-ULK1-modulated autophagic pathway in breast cancer cells.
FL-411 induces ACD pathways involved in HMGB1, VDAC1/2, and eEF2.
FL-411 displays a therapeutic potential on both breast cancer xenograft mouse and zebrafish models.
