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FLX4

Chemical Structure : FLX4

CAS No.: 2325649-36-1

FLX4

Catalog No.: PC-22878Not For Human Use, Lab Use Only.

FLX4 is a potent, selective and allosteric inhibitor of USP7 with IC50 of <1 uM.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

FLX4 is a potent, selective and allosteric inhibitor of USP7 with IC50 of <1 uM.

Physicochemical Properties

M.Wt 583.00
Formula C26H23ClF4N4O3S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3-((7-(5-chloro-2-(((3S,4R)-4-fluoropiperidin-3-yl)oxy)-3-methylphenyl)thieno[3,2-b]pyridin-2-yl)methyl)-1-(2,2,2-trifluoroethyl)pyrimidine-2,4(1H,3H)-dione

References

1. Biannic, B.; Han, X.; Hu, D. X., Ubiquitin-Specific-Processing Protease 7 (Usp7) Modulators and Uses Thereof. U.S. US20190142834A1, 2019.

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