FO-4-15

Chemical Structure : FO-4-15

Catalog No.: PC-22952Not For Human Use, Lab Use Only.

FO-4-15 is a small molecule taregting mGluR1 with low cytotoxicity and anti-H2O2 effect, significantly reduces Aβ accumulation, Tau hyper-phosphorylation, and synaptic impairments in 3×Tg mice, activates mGluR1/CaMKIIα pathway.

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Biological Activity

Physicochemical Properties

M.Wt	424.48
Formula	C21H20N4O4S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	3-(furan-2-yl)-5-((4-(naphthalen-2-ylsulfonyl)piperazin-1-yl)methyl)-1,2,4-oxadiazole

References

1. Luo ZH, et al. Acta Pharmacol Sin. 2024 Aug 16. doi: 10.1038/s41401-024-01362-0.

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FO-4-15

Biological Activity

Physicochemical Properties

References

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