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FR900098 sodium

Chemical Structure : FR900098 sodium

CAS No.: 73226-73-0

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FR900098 sodium (FR 900098)

Catalog No.: PC-62608Not For Human Use, Lab Use Only.

FR900098 sodium is a derivative of fosmidomycin that inhibits DOXP reductoisomerase, demonstrates antimalarial activity with IC50 of 170, 170, and 90 nM for HB3, A2, and Dd2 P. falciparum strains, respectively.

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    Biological Activity

    FR900098 sodium is a derivative of fosmidomycin that inhibits DOXP reductoisomerase, demonstrates antimalarial activity with IC50 of 170, 170, and 90 nM for HB3, A2, and Dd2 P. falciparum strains, respectively.

    Physicochemical Properties

    M.Wt 219.109
    Formula C5H11NNaO5P
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    P-[3-(acetylhydroxyamino)propyl]-phosphonic acid, monosodium salt

    References

    1. Jomaa H, et al. Science. 1999 Sep 3;285(5433):1573-6.

    2. Reichenberg A, et al. Bioorg Med Chem Lett. 2001 Mar 26;11(6):833-5.

    3. Okuhara M, et al. J Antibiot (Tokyo). 1980 Jan;33(1):13-7.

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