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Chemical Structure : FTO-02
Catalog No.: PC-72225Not For Human Use, Lab Use Only.
FTO-02 is a potent, selective, competitive small molecule inhibitor of m6A-RNA demethylase FTO with IC50 of 2.18 uM, 40-fold selectivity over RNA demethylase ALKBH5 (ALKBH5, IC50=85.5 uM).
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FTO-02 is a potent, selective, competitive small molecule inhibitor of m6A-RNA demethylase FTO with IC50 of 2.18 uM, 40-fold selectivity over RNA demethylase ALKBH5 (ALKBH5, IC50=85.5 uM).
| M.Wt | 252.273 | |
| Formula | C15H12N2O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Sarah Huff, et al. ACS Chem Biol. 2021 Feb 19;16(2):324-333.
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