FTO inhibitor Dac85

Chemical Structure : FTO inhibitor Dac85

Catalog No.: PC-23897Not For Human Use, Lab Use Only.

FTO inhibitor Dac85 is a small molecule inhibitor of fat mass and obesity-associated protein (FTO) with IC50 of 0.7 uM, displays strong antiproliferative effect on AML cells.

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Biological Activity

FTO inhibitor Dac85 is a small molecule inhibitor of fat mass and obesity-associated protein (FTO) with IC50 of 0.7 uM, displays strong antiproliferative effect on AML cells.

Physicochemical Properties

M.Wt	375.78
Formula	C18H15ClFN3O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-((2-chloro-4-(3,5-dimethylisoxazol-4-yl)-6-fluorophenyl)amino)-N-hydroxybenzamide

References

1. Xiao P, et al. J Med Chem. 2023 Jul 27;66(14):9731-9752.

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