FTO inhibitor FB23

Chemical Structure : FTO inhibitor FB23

CAS No.: 2243736-35-6

Catalog No.: PC-22847Not For Human Use, Lab Use Only.

FTO inhibitor FB23 is a potent and selective FTO demethylase inhibitor with IC50 of 60 nM, directly binds to FTO and selectively inhibits FTO's mRNA N6-methyladenosine (m6A) demethylase activity.

Packing	Price	Stock
5 mg	$128	In stock
10 mg	$188	In stock
25 mg	$298	In stock

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Biological Activity

FTO inhibitor FB23 is a potent and selective FTO demethylase inhibitor with IC50 of 60 nM, directly binds to FTO and selectively inhibits FTO's mRNA N6-methyladenosine (m6A) demethylase activity.

Physicochemical Properties

M.Wt	377.22
Formula	C18H14Cl2N2O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-((2,6-Dichloro-4-(3,5-dimethylisoxazol-4-yl)phenyl)amino)benzoic acid

References

1. Yue Huang, et al. Cancer Cell. 2019 Apr 15;35(4):677-691.e10.

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