Chemical Structure : FTO inhibitor FB23
CAS No.: 2243736-35-6
Catalog No.: PC-22847Not For Human Use, Lab Use Only.
FTO inhibitor FB23 is a potent and selective FTO demethylase inhibitor with IC50 of 60 nM, directly binds to FTO and selectively inhibits FTO's mRNA N6-methyladenosine (m6A) demethylase activity.
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FTO inhibitor FB23 is a potent and selective FTO demethylase inhibitor with IC50 of 60 nM, directly binds to FTO and selectively inhibits FTO's mRNA N6-methyladenosine (m6A) demethylase activity.
M.Wt | 377.22 | |
Formula | C18H14Cl2N2O3 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
2-((2,6-Dichloro-4-(3,5-dimethylisoxazol-4-yl)phenyl)amino)benzoic acid |
1. Yue Huang, et al. Cancer Cell. 2019 Apr 15;35(4):677-691.e10.
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