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FUBP1-IN-1

Chemical Structure : FUBP1-IN-1

CAS No.: 883003-62-1

FUBP1-IN-1

Catalog No.: PC-26585Not For Human Use, Lab Use Only.

FUBP1-IN-1 is a small molecule inhibitor of transcriptional regulator FUSE binding protein 1 (FUBP1), inhibits the binding of FUBP1 to the FUSE sequence with IC50 of 11.0 uM, reduces cell expansion and induces of cell death in hepatocellular carcinoma cells.

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Biological Activity

FUBP1-IN-1 is a small molecule inhibitor of transcriptional regulator FUSE binding protein 1 (FUBP1), inhibits the binding of FUBP1 to the FUSE sequence with IC50 of 11.0 uM, reduces cell expansion and induces of cell death in hepatocellular carcinoma cells.

Physicochemical Properties

M.Wt 405.40
Formula C19H14F3N3O2S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

5-(3,4-Dimethoxyphenyl)-2-(thiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine

References

1. Hauck S, et al. Bioorg Med Chem. 2016 Nov 15;24(22):5717-5729.

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