FZD7 NAM C407

Chemical Structure : FZD7 NAM C407

Catalog No.: PC-25909Not For Human Use, Lab Use Only.

FZD7 NAM C407 is a small molecule negative allosteric modulator (NAM) of Frizzled 7 (FZD7), C407 binds within the 7TMD of FZD7, C407 is a NAM of WNT-induced signaling and FZD-mediated WNT/β-catenin signaling.

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Biological Activity

Physicochemical Properties

M.Wt	389.40
Formula	C18H16FN3O4S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	ethyl 3-(2-((2-fluorophenyl)amino)-2-oxoethyl)-5-methyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidine-6-carboxylate

References

1. Scharf MM, et al. Nat Commun. 2025 Dec 14;16(1):11138.

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FZD7 NAM C407

Biological Activity

Physicochemical Properties

References

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