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Fenretinide

Chemical Structure : Fenretinide

CAS No.: 65646-68-6

Fenretinide (NSC 374551;4-HPR;4-Hydroxyphenyl retinamide)

Catalog No.: PC-35992Not For Human Use, Lab Use Only.

Fenretinide (NSC 374551, 4-HPR, 4-Hydroxyphenyl retinamide) is a synthetic retinoid derivative with potential antineoplastic and chemopreventive activities, binds to and activates RARs, thereby inducing cell differentiation and apoptosis in some tumor cell types..

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Biological Activity

Fenretinide (NSC 374551, 4-HPR, 4-Hydroxyphenyl retinamide) is a synthetic retinoid derivative with potential antineoplastic and chemopreventive activities, binds to and activates RARs, thereby inducing cell differentiation and apoptosis in some tumor cell types.

Physicochemical Properties

M.Wt 391.555
Formula C26H33NO2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(2E,4E,6E,8E)-N-(4-hydroxyphenyl)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenamide

References

1. Levine L. Prostaglandins Med. 1980 May;4(5):285-96.

2. Bertram JS. Cancer Res. 1980 Sep;40(9):3141-6.

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