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Fexinidazole

Chemical Structure : Fexinidazole

CAS No.: 59729-37-2

Fexinidazole (HOE 239)

Catalog No.: PC-25297Not For Human Use, Lab Use Only.

Fexinidazole (HOE 239) is an orally active, potent nitroimidazole antitrypanosomal agent, shows trypanocidal activity against T. brucei subspecies and strains with IC50 of 0.7-3.3 uM, has the potential for human sleeping sickness (HAT) caused by infection with T. brucei.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Fexinidazole (HOE 239) is an orally active, potent nitroimidazole antitrypanosomal agent, shows trypanocidal activity against T. brucei subspecies and strains with IC50 of 0.7-3.3 uM, has the potential for human sleeping sickness (HAT) caused by infection with T. brucei.

Physicochemical Properties

M.Wt 279.31
Formula C12H13N3O3S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1-Methyl-2-((4-(methylthio)phenoxy)methyl)-5-nitro-1H-imidazole

References

1. Kaiser M, et al. Antimicrob Agents Chemother. 2011 Dec;55(12):5602-8.

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