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Chemical Structure : Fidarestat
CAS No.: 136087-85-9
Catalog No.: PC-61992Not For Human Use, Lab Use Only.
Fidarestat (SNK860) is a potent, selective aldose reductase inhibitor with IC50 of 26 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $158 | In stock | |
| 10 mg | $248 | In stock | |
| 25 mg | $438 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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Fidarestat (SNK860) is a potent, selective aldose reductase inhibitor with IC50 of 26 nM.
Fidarestat (SNK860) shows little to no inhibition against AKR1B10 和 V301L AKR1B10.
Fidarestat (SNK860) improves motor nerve conduction velocity (MNCV) and metabolic abnormalities in sciatic nerve were investigated in acute STZ-induced diabetic rats.
| M.Wt | 279.227 | |
| Formula | C12H10FN3O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
(2S,4S)-6-fluoro-2',5'-dioxospiro[2,3-dihydrochromene-4,4'-imidazolidine]-2-carboxamide |
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1. Mizuno K, et al. Metabolism. 1992 Oct;41(10):1081-6.
2. Hotta N, et al. Exp Physiol. 1995 Nov;80(6):981-9.
3. Kawamura T, et al. Diabet Med. 1995 May;12(5):392-6.
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