Chemical Structure : Fidarestat
CAS No.:
136087-85-9
Fidarestat
(SNK-860, SNK860)
Catalog No. : PC-61992Not For Human Use, Lab Use Only.
Fidarestat (SNK860) is a potent, selective aldose reductase inhibitor with IC50 of 26 nM.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-6199201
Biological Activity
Fidarestat (SNK860) is a potent, selective aldose reductase inhibitor with IC50 of 26 nM.
Physicochemical Properties
M.Wt
279.227
Formula
C12H10FN3O4
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
(2S,4S)-6-fluoro-2',5'-dioxospiro[2,3-dihydrochromene-4,4'-imidazolidine]-2-carboxamide
References
1. Mizuno K, et al. Metabolism. 1992 Oct;41(10):1081-6.
2. Hotta N, et al. Exp Physiol. 1995 Nov;80(6):981-9.
3. Kawamura T, et al. Diabet Med. 1995 May;12(5):392-6.
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