Chemical Structure : Filapixant
CAS No.: 1948232-63-0
Catalog No.: PC-20738Not For Human Use, Lab Use Only.
Filapixant (BAY1902607) is a potent, selective P2X3 receptor antagonist, shows a substantially higher in vitro selectivity for P2X3 over P2X2 when compared with Eliapixant (BAY1817080, Cat# PC-72754).
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Filapixant (BAY1902607) is a potent, selective P2X3 receptor antagonist, shows a substantially higher in vitro selectivity for P2X3 over P2X2 when compared with Eliapixant (BAY1817080, Cat# PC-72754).
Filapixant has a higher in vitro selectivity for P2X3 than other receptor antagonists such as gefapixant, or even eliapixant.
| M.Wt | 521.56 | |
| Formula | C24H26F3N5O3S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
3-(((R)-4-methylmorpholin-2-yl)methoxy)-5-(5-methylthiazol-2-yl)-N-((R)-1-(2-(trifluoromethyl)pyrimidin-5-yl)ethyl)benzamide |
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1. Davenport AJ, et, al. 1,3-thiazol-2-yl substituted benzamides. WO2016091776A1.

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