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Filovirus inhibitor compd-A

Chemical Structure : Filovirus inhibitor compd-A

CAS No.: 667432-48-6

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Filovirus inhibitor compd-A

Catalog No.: PC-38559Not For Human Use, Lab Use Only.

Filovirus inhibitor compd-A is a small molecule filovirus entry inhibitor targeting the endosomal receptor NPC1 binding site, shows potent inhibitory activity against both Ebola and Marburg viruses with IC50 of 0.86 uM against pseudotyped Marburg virus entry.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    Filovirus inhibitor compd-A is a small molecule filovirus entry inhibitor targeting the endosomal receptor NPC1 binding site, shows potent inhibitory activity against both Ebola and Marburg viruses with IC50 of 0.86 uM against pseudotyped Marburg virus entry.

    Physicochemical Properties

    M.Wt 398.458
    Formula C26H22O4
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    7-(2-(3,4-dimethylphenyl)-2-oxo-1-phenylethoxy)-4-methyl-2H-chromen-2-one

    References

    1. Leah Liu Wang, et al. Antiviral Res. 2021 May;189:105059.

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