Flumazenil | GABAA antagonist | Probechem Biochemicals

Chemical Structure : Flumazenil

CAS No.: 78755-81-4

Flumazenil (Ro 15-1788)

Catalog No.: PC-24505Not For Human Use, Lab Use Only.

Flumazenil is a central benzodiazepine receptor (IC50=9.91 nM) and competitive GABAA receptor antagonist, reverses the sedative effects of benzodiazepines on the central nervous system.

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10 mg	$38	In stock
50 mg	$88	In stock
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Biological Activity

Flumazenil is a central benzodiazepine receptor (IC50=9.91 nM) and competitive GABAA receptor antagonist, reverses the sedative effects of benzodiazepines on the central nervous system.

Physicochemical Properties

M.Wt	303.29
Formula	C15H14FN3O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	Ethyl 8-fluoro-5-methyl-6-oxo-5,6-dihydro-4H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxylate

References

1. Zhang LM, et al. Neuropharmacology. 2014 Jun;81:116-25.

2. Hunkeler W, et al. Nature. 1981 Apr 9;290(5806):514-6. doi: 10.1038/290514a0.

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Flumazenil (Ro 15-1788)

Biological Activity

Physicochemical Properties

References

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