Forskolin | Adenylate cyclase activator

Chemical Structure : Forskolin

CAS No.: 66575-29-9

Forskolin (Coleonol, Colforsin, HL362)

Catalog No.: PC-28416Not For Human Use, Lab Use Only.

Forskolin (Coleonol, Colforsin) is a potent adenylate cyclase activator with IC50 of 41 nM and EC50 of 0.5 uM for type I adenylyl cyclase, is an inducer of intracellular cAMP formation.

Packing	Price	Stock
25mg	$88	In stock
50 mg	$128	In stock
100 mg	$198	In stock
250 mg		Get quote

Get Quotation Now

* Please select Quantity before adding items.

or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Biological Activity

Forskolin (Coleonol, Colforsin) is a potent adenylate cyclase activator with IC50 of 41 nM and EC50 of 0.5 uM for type I adenylyl cyclase, is an inducer of intracellular cAMP formation.
Forskolin induces differentiation of various cell types and activates pregnane X receptor (PXR) and FXR.
Forskolin exerts a inotropic effect on the heart, and has platelet antiaggregatory and antihypertensive actions.
Forskolin also induces autophagy.

Physicochemical Properties

M.Wt	410.51
Formula	C22H34O7
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(3R,4aR,5S,6S,6aS,10S,10aR,10bS)-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-3-vinyldodecahydro-1H-benzo[f]chromen-5-yl acetate

References

1. Robbins JD, et al. J Med Chem. 1996 Jul 5;39(14):2745-52.

2. Matsumiya W, et al. Invest Ophthalmol Vis Sci. 2012 Dec 7;53(13):8029-35.

3. Mayati A, et al. Sci Rep. 2018 Oct 31;8(1):16115.

Forskolin (Coleonol, Colforsin, HL362)

Biological Activity

Physicochemical Properties

References

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

Get Quote

* Indicates a Required FieldYour information is safe with us.