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Fulzerasib

Chemical Structure : Fulzerasib

CAS No.: 2641747-54-6

Fulzerasib (IBI351, IBI-351, GFH925)

Catalog No.: PC-20037Not For Human Use, Lab Use Only.

Fulzerasib (IBI351, IBI-351) is a potent covalent and irreversible inhibitor of KRAS G12C.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    Fulzerasib (IBI351, IBI-351, GFH925) is a potent covalent and irreversible inhibitor of KRAS G12C.

    Physicochemical Properties

    M.Wt 617.08
    Formula C32H30ClFN6O4
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (4aR)-3-acryloyl-11-chloro-10-(2-fluoro-6-hydroxyphenyl)-8-(2-isopropyl-4-methylpyridin-3-yl)-6-methyl-2,3,4,4a,6,8-hexahydro-1H-pyrazino[1',2':4,5]pyrazino[2,3-c][1,8]naphthyridine-5,7-dione

    References

    1. Patent WO2021083167 A1

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