Furin inhibitor 9

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Chemical Structure : Furin inhibitor 9

Catalog No.: PC-26216Not For Human Use, Lab Use Only.

Furin inhibitor 9 is a highly potent, small molecule inhibitor of proprotein convertase (PC) furin with Ki of 12.4 nM, weakly inhibits the structurally related PC7 with Ki of 278 nM, shows antiviral potency against the furin-dependent H7N7 influenza A strain SC35M.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Physicochemical Properties

M.Wt	913.70
Formula	C32H44Cl2N4O.3C2HF3O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	Acetamide, N-[[1-[[5-([4,4′-bipiperidin]-1-ylmethyl)-3′,5′-dichloro[1,1′-biphenyl]-3-yl]methyl]-4-piperidinyl]methyl]-, 2,2,2-trifluoroacetate (1:3)

References

1. Lange RW, et al. J Med Chem. 2025 Nov 30. doi: 10.1021/acs.jmedchem.5c02157.

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